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Review 2013

Relevance of signaling molecules for apoptosis induction on influenza A virus replication

Iwai, Atsushi; Shiozaki, Takuya; Miyazaki, Tadaaki · Biochemical and Biophysical Research Communications · DOI: 10.1016/j.bbrc.2013.10.100
Read Original Paper DOI: 10.1016/j.bbrc.2013.10.100
Research Archive
TL;DR — Key Findings
  • Influenza proteins can manipulate host apoptosis pathways.
  • Those changes may affect replication and disease severity.
  • No beta-glucan or Aureobasidium treatment was studied.

Abstract

This review examines how influenza A virus proteins manipulate host apoptosis pathways to support viral replication and how those changes can contribute to disease severity. It summarizes host and viral signaling molecules involved in cell death and extracellular immune responses. The paper is mechanistic background on influenza pathogenesis and does not test beta-glucan, Aureobasidium pullulans, or a treatment.

Summary

Summary

Scope

Review of apoptosis-related signaling in influenza replication and disease.

Interpretation

The paper provides mechanistic background only and contains no beta-glucan intervention.

AI-generated summary for accessibility. Always refer to the original paper.

Citation

Iwai, Atsushi; Shiozaki, Takuya; Miyazaki, Tadaaki. Relevance of signaling molecules for apoptosis induction on influenza A virus replication. Biochemical and Biophysical Research Communications. 2013. DOI: 10.1016/j.bbrc.2013.10.100.

Study Details
Study Type
Review
Published
2013
Journal
Biochemical and Biophysical Research Communications
Authors
Iwai, Atsushi; Shiozaki, Takuya; Miyazaki, Tadaaki
DOI
10.1016/j.bbrc.2013.10.100
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