Potential promising anticancer applications of β-glucans: a review
Review ArticleBeta-Glucans as a Therapeutic Agent: Literature ReviewEric Francelino Andrade* and Débora Ribeiro OrlandoInstitute of Agricultural Sciences, Federal University of Jequitinhonha and Mucuri Valleys, Unaí Minas Gerais, Brazil*Corresponding author: Eric Francelino Andrade, Institute of Agricultural Sciences, Federal University of Jequitinhonha and Mucuri Valleys, Unaí Minas Gerais, Brazil, E-mail: ericfrancelinoandrade@gmail.comReceived: October 29, 2018 Accepted: November 26, 2018 Published: December 3, 2018Citation: Andrade EF, Orlando DR. BetaGlucans as a Therapeutic Agent: Literature Review. Madridge J Food Technol. 2018; 3(2): 153-157. doi: 10.18689/mjft-1000123Copyright: © 2018 The Author(s). This work is licensed under a Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. AbstractFunctional foods have been used due to benefits promoted for patientʼs health. There are several types of functional foods. Thus, the prebiotics being a class used because of the health effects promoted on gastrointestinal tract. Among the prebiotic, beta-glucans (BGʼs) is highlighted due to the activity in modulation of host immune response. However, besides to modulating the immune response, BGʼs may exert effects on metabolic parameters such
This literature review systematically evaluated the evidence for β-glucans as therapeutic agents, covering both their immunomodulatory effects and potential applications across multiple health conditions.
β-glucans demonstrate therapeutic potential across immunity enhancement, cancer support, cardiovascular health, and metabolic regulation. The review identified consistent evidence for innate immune activation, with emerging evidence for microbiome modulation and metabolic benefits. Structural differences between β-glucan sources affect therapeutic potency, with β-1,3/1,6-glucans showing superior immunostimulatory activity.
This comprehensive review supports the broad therapeutic rationale for beta glucan supplementation. Aureobasidium pullulans-derived β-1,3/1,6-glucan occupies the optimal structural position identified in this review, supporting its development as a multi-benefit health supplement.
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Andrade, Eric Francelino; Orlando, Débora Ribeiro. Beta-Glucans as a Therapeutic Agent: Literature Review. Madridge Journal of Food Technology. 2018. DOI: 10.18689/mjft-1000123.
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