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patent 2023

Biological healing accelerator – Japan (License No. 5331482)

Iwai A., Uchiyama H. · Japanese Patent Office
Research Archive
TL;DR — Key Findings
  • AP β-glucan demonstrated biological healing acceleration, potentially through macrophage-mediated repair.
  • Enhanced macrophage function accelerates wound healing through improved clearance and growth factor production.
  • Healing acceleration extends AP-glucan's profile into wound healing and regenerative medicine applications.

Abstract

Biological healing accelerator – Japan (License No. 5331482)

Patent Details

Country of RegistrationJapan

Patent No.No. 5331482Registration DateAugust 02, 2013Remarks※ Reduction of side effects of anti-cancer drugs

Currently, Aureobasidium (black yeast) culture medium (hereafter referred to as “Aureo culture medium”) has been approved in Japan, Europe (UK, France, Germany), China, Hong Kong, Taiwan, and Thailand to reduce the side effects of anticancer drugs and to promote healing of erythema caused by burn wounds.

Summary

Summary

Background

This Japanese biological healing accelerator patent (License No.) covers Aureobasidium pullulans-derived β-glucan for accelerating biological healing processes, reflecting AP-glucan's potential tissue repair applications.

Key Findings

AP β-glucan demonstrated biological healing acceleration properties, likely through its immunostimulatory effects on macrophage function and anti-inflammatory activity. Enhanced macrophage activity in wound sites could accelerate tissue repair through improved debris clearance and growth factor production.

Relevance to Aureobasidium Beta Glucan Research

Tissue healing applications extend AP-glucan's therapeutic profile into wound healing and regenerative medicine contexts. The immune-tissue repair connection positions AP β-glucan as a potential multi-modal therapeutic supporting both immune defense and tissue recovery.

Citation

Iwai A., Uchiyama H.. Biological healing accelerator – Japan (License No. 5331482). Japanese Patent Office. 2023.

Study Details
Study Type
patent
Published
2023
Journal
Japanese Patent Office
Authors
Iwai A., Uchiyama H.
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