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Botryosphaeran – A Fungal Exopolysaccharide of the (1→3)(1→6)-β-D-Glucan Kind: Structure and Biological Functions

Botryosphaeran – A Fungal Exopolysaccharide of the (1→3)(1→6)-β-D-Glucan Kind: Structure and Biological Functions   Abstract A fungal isolate (MAMB-05) from a stem canker on a eucalypt tree, molecularly classified as Botryosphaeria rhodina, produced an exopolysaccharide (EPS) of the β-D-glucan type when cultivated on glucose by submerged fermentation. Isolation and elucidation of

Inhibition of tumor growth by β-glucans through promoting CD4+ T cell immunomodulation and neutrophil-killing in mice

Highlights Abstract β-glucans are polysaccharides comprising β-D-glucoses with various bioactivities. Herein, we extracted three β-glucans from Lentinus edodes with different sources and assessed their antitumor activities on a mice model with intragastric, intraperitoneal and intratumoral injection. Three polysaccharides were shown to have the same chemical structure of β-(1,3)-glucan with β-(1,6) branches, and