Highlights Abstract Polysaccharides from extracellular (PSEX), cell wall (PSCW), and intracellular (PSIN) fractions of Aureobasidium pullulans CGMCC19650 were extracted and purified, respectively. Based on chemical composition analysis and spectral characterization using Fourier-transform infrared (FT-IR) and nuclear magnetic resonance (NMR) spectroscopy, it was confirmed that the three polysaccharides are β-1,3-1,6-glucans. However, results of molecular weight analysis, Congo red
Beta (β)-glucan as Microbial Polymer with Nutraceutical Potential Summary Nutraceuticals provide significant potential in enhancing health and mitigating ailments, rendering them a vital inclusion in the contemporary healthcare domain. Nutraceutical polymers derived from microbes including bacteria, fungi, and microβalgae are one of the versatile and sustainable bioactive compounds with
Highlights •β-glucan receptors are closely related to these antitumor effects of β-glucan. •In antitumor immunity, β-glucan is not only effective in simple immune activation. •β-glucan modulates immune cells to attack tumor cells that escaped from immunity. •β-glucan mimics tumor-specific sugar chains expressed on the surface of tumor cells. •β-glucan can directly induce cell death
Abstract β-(1→3)-Glucans can be found as structural polysaccharides in cereals, in algae or as exo-polysaccharides secreted on the surfaces of mushrooms or fungi. Research has now established that β-(1→3)-glucans can trigger different immune responses and act as efficient immunostimulating agents. They constitute prevalent sources of carbons for microorganisms after subsequent