Abstract Aureobasidium pullulans (A. pullulans), a commonly found yeast-like fungus, exhibits adaptability to a wide range of pH environments. However, the specific mechanisms and regulatory pathways through which A. pullulans respond to external pH remain to be fully understood. In this study, we first sequenced the whole genome of A. pullulans using Nanopore technology and
5-Demethylnobiletin is the active ingredient in citrus polymethoxyflavones that could inhibit the proliferation of several tumor cells. However, the anti-tumor effect of 5-Demethylnobiletin on glioblastoma and the underlying molecular mechanisms are remains unknown. In our study, 5-Demethylnobiletin markedly inhibited the viability, migration and invasion of glioblastoma U87-MG, A172 and U251
Abstract The black yeast-like fungi Aureobasidium spp. are ubiquitous microorganisms found in a wide variety of extreme and benign environments as saprophytes, endophytes, and pathogens. Since this diverse genus includes species with potential uses in agriculture and the food industry, it is important that we explore their evolution and spread in the
Highlights Abstract Aureobasidium spp. are the dimorphic fungi which have both major yeast cells and minor filamentous cells. Different strains of Aureobasidium spp. can synthesize different enzymes for utilization of a wide range of substrates including various wastes. Aureobasidium spp. also can synthesize many natural products such as pullulan, β-glucan, polymalate, liamocins, siderophores and melanin which have many applications in various sectors of biotechnology. Furthermore, their