Oral administration of the β-glucan produced by Aureobasidium pullulans ameliorates development of atherosclerosis in apolipoprotein E deficient mice Highlights •Aureobasidium pullulans-derived β-glucan (AP-PG) is known to be an immunomodulator. •Apolipoprotein E deficient (ApoE) mice spontaneously develop atherosclerosis. •AP-PG is effective in ameliorating development of atherosclerosis in the model mice. •AP-PG administration reduces oxidized low-density lipoprotein cholesterol levels. •Oral administration of